Human Metabolome Technologies America Inc.

Targeted Glycolytic Panel- C-SCOPE

C-SCOPE consists of a targeted quantitative panel of 116 metabolites in the glycolytic pathway including the pentose phosphate pathway, TCA cycle, amino acids and urea cycle. Typically used to study cancer, Warburg effect and mitochondrial metabolism.

C-SCOPE: Targeted Glycolytic Panel and Pathway

Download HMT C-SCOPE Metabolite Panel
One of the unique features of Capillary electrophoresis is the ability to measure and resolve polar metabolites. In the C-SCOPE panel, HMT can quantitate isoleucine/ Leucine, DHAP / Glyceraldehyde-3P, 2-Phosphoglycerate/3-phosphoglyercate, citrate/isocitrate, Ribose-5P/Ribulose 5P, Fructose-6P/Glucose-6P/Glucose-1P along with many tri, di and mono phosphorylated nucleic acids, pyruvate and lactic acid. This makes CSOPE ideal for measuring glycolysis in cells, often used to study the Warburg effect in cancer cells. Typically, a few million cells are required for a C-SCOPE analysis, that includes pathway mapping and biological interpretations.

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