Overview of Services
- Study design
- Sample preparation and shipping
- Extraction of metabolites
- Measurements / Statistical analysis
- Reporting (4 – 8 weeks)
- Biological interpretation
Our study reports include not only raw data but also supportive information assisting your understanding of observed metabolic changes. Further, experienced biochemist will support data interpretation by follow up discussions.
Metabolomics, a comprehensive analysis of small molecular compounds in biological samples, is a powerful tool because almost all biological phenomena result in changes in an organismal or cellular metabolic state. However, grasping global changes in metabolism is not easy because it requires the precise measurement of these compounds with a variety of physical and chemical properties.
Central metabolism, which includes bioenergetics and protein / nucleotide turnover is involved in most cellular systems, and therefore is regarded as core to understanding systems biology. Recent research has revealed the importance of primary metabolism in several areas including oncology, stem cell biology, bioprocessing etc.
One key to understanding cellular metabolomics lies in the ability to accurately determine the specific metabolic pathways that are employed. The use of isotopically labeled substrates allows for the tracing of metabolites and the elucidation of active metabolic pathways.
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